White matter microstructural integrity in recovering alcoholic population

D. Sugumar, Chandra Kumar Dixit, Miguel A. Saavedra-Lopez, Ronald M. Hernandez, Abhishek Madduri, Bhasker Pant

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Adolescents are often the first to experiment with drinking, a phase considered to be essential in neurogenesis. The developing brain is more prone to the impact of drinking. Whereas the intellectual disadvantages related to adolescent alcohol consumption were extensively established, the brain foundations underlying physiology are still poorly known. Brain white matter was already proposed as the principal source of liquor injury, and diffusion tensor imaging (DTI) provides for inside the laboratory measurement of brain structure viability. This article combines findings from bridge and continuous DTI investigations that show hippocampal pathways, notably those assumed to be important in cognitive performance, keep growing during adolescent years. Several DTI studies show a favorable relationship among brain structure intact and neuropsychological ability, as well as the negative consequences of long-term alcohol dependency on hippocampal stability in adulthood. We present a thorough evaluation of DTI research investigating the association among teenage alcohol consumption and brain structure preservation. The majority of such investigations' findings shows that heavy drinking is related to decreased white matter stability, notably in the supra longitudinal fasciculus (SLF), and some evidence shows that somehow this association may be altered by gender. We end by noting the study's bewilders and limits and recommending additional relevant studies.

Original languageEnglish
Title of host publicationInternational Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735444430
DOIs
StatePublished - 25 Apr 2023
Externally publishedYes
Event2022 International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022 - Chennai, India
Duration: 21 Mar 202225 Mar 2022

Publication series

NameAIP Conference Proceedings
Volume2603
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference2022 International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022
Country/TerritoryIndia
CityChennai
Period21/03/2225/03/22

Bibliographical note

Publisher Copyright:
© 2023 Author(s).

Keywords

  • adolescence
  • alcohol
  • cerebral white matter
  • cognitive behavior
  • drug abuse

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